sho_shweet

ammi ji abbu ji bhai ji bhabhi ji api ji choty ji bry ji sb ji

Thandi thandi hawa chali ... kha lo beta mong phali

Fantastic ^_^

soch rhi hun ab isy tang krun :D

without bilawajah dosrun ko tang krna :v

Movie may be :3

Perfect

"Thinking" that why sometimes I feel myself misplaced in the world

Secret in their eyes

روز افتاد نئی دل پہ گزر تی ہے مگر روز کے روز یہ قصے نہیں لکھے جاتے

ha ha ha -_-

good

We've never seen the CRISPR gene-editing tool used like this before. Scientists have turned a Japanese garden plant from violet to white by disrupting a single gene - yet more evidence of the huge potential that CRISPR holds. The modified flower is the Japanese morning glory plant (the Ipomoea nil or Pharbitis nil), with researchers targeting only the gene responsible for flower colour without affecting the rest of the plant. But the potential here goes far beyond the cosmetic. If you're new to CRISPR/Cas9 - the Cas9 enzyme is responsible for doing the DNA cutting - it lets scientists cut and paste genes with incredible precision, allowing for some pretty deep biological engineering. While many are concerned about how these tools could be misused, they could also do a lot of good. We've already seen it used to edit out genes causing disease in animals, though there are ethical questions about its possible future use in humans. Now this team, from institutions across Japan, says the CRISPR/Cas9 technique is going to make a huge difference in the study and manipulation of plants. "To our knowledge, this report is the first concerning flower colour changes in higher plants using CRISPR/Cas9 technology," writes the team of researchers. The morning glory plant was chosen for this particular experiment as it's already part of the National BioResource Project (NBRP) in Japan – that means scientists already know a lot about its genetic coding, and the DNA blueprints are already available. The team targeted the gene responsible for the colour of the plant's flowers, the dihydroflavonol-4-reductase-B (DFR-B) gene. With two other very closely related genes sitting either side of DFR-B, the challenge was to use CRISPR/Cas9 to snip out the right DNA strands very specifically without affecting the rest of the plant. The enzyme produced by DFR-B is known to be responsible for producing the colour pigment anthocyanin, so shutting it off should turn the flowers white – and so it proved. Around 75 percent of the treated plant embryos grew up to flower with white rather than violet petals, and further analysis of the neighbouring genes showed no mutations, a testament to the accuracy of CRISPR/Cas9. The study has consequences beyond potentially enabling you to colour your flower beds to order, because some of the next generation of plants – which also grew up with white flowers – showed no signs of the artificially introduced DNA. That raises interesting questions about how our newly found gene editing powers could permanently change the course of nature, no matter how good or bad our intentions. For now though, the scientists are promoting their study as a way of showing the accuracy and the potential of CRISPR/Cas9: the morning glory plant was introduced to Japan in the 8th century AD, and it wasn't until the 17th century that a white version appeared as the result of a genetic mutation. What nature took around 850 years to achieve, CRISPR/Cas9 managed in less than 12 months, and that's both exciting and a little scary. "The successful results of the present study will facilitate the modification of flower colours and shapes with targeted mutagenesis in Ipomoea nil and other ornamental flowers or vegetables," conclude the researchers. The research has been published in Scientific Reports.

nothing

fine

If you raised a newly born baby inside a bubble, you took care of him, provided him food and cleaned him, but made sure he doesn’t hear a single word from anybody. When children subjected to such conditions become able to speak, which language will they develop? In other words, what is the natural language of mankind? The first experiment to learn about the innate language of mankind was conducted around 2,700 years ago. The Egyptian pharaoh Psamtik I ordered two babies to be raised in isolation. After the experiment was done, one of the children babbled something that sounded like “bekos”, a word that describes “bread” in the ancient Phrygian language. So, it was declared by the pharaoh that Phrygian was the innate language of all mankind. In the 13th century, Emperor Frederick II decided to take this experiment much further and raise the children without human interaction. The babies were only fed and never talked to or touched. Unfortunately, they couldn’t survive and died from neglect. In the 15th century, King James IV of Scotland made a mute woman raise babies alone on an island. He reported that those babies ended up speaking perfect Hebrew. But historians were skeptical of these claims. When the same experiment was repeated again by the Mughal emperor Akbar, he came to the conclusion that speech arose from hearing, thus children raised without hearing human speech would become mute. Now, all these experiments sound interesting and cruel at the same time, but modern science has already revealed how we develop language. As a matter of fact we start learning language at the 4th month while still in womb. So, whatever the mother speaks or whatever you say around a pregnant woman will be recognized by the baby. Some of the words will be retained and will likely be used after birth. Remember that the sound-processing parts of baby’s brain become active in the last three months of pregnancy. And since sound can travel well through the mother's abdomen, it’s fair to say that the baby can recognize any speech coming from the outside world. What’s even more interesting is that babies can immediately differentiate between sounds from their native language and a foreign language just a few hours after their birth! A recent study found that babies can even distinguish between two languages one month BEFORE they are born and respond differently to hearing a language they are not familiar with. When they hear a foreign language they’re not familiar with, their heart rate changes. This means they recognize a rhythmical difference between the sound of their native language and that of a foreign language. Ohh! And BTW, babies do enjoy music while still in the womb. So, please avoid listening to Justin Bieber during pregnancy …… or anytime for that matter. Sources: http://www.pnas.org/content/110/37/15145 http://ilabs.washington.edu/sites/default/files/Abstract.pdf https://insights.ovid.com/crossref?an=00001756-201708010-00004 http://www.iupress.indiana.edu/product_info.php?products_id=21102 http://sourcebooks.fordham.edu/halsall/source/salimbene1.html http://www.digma.com/digma-images/video-scripts/fredericks_experiment.pdf

لکیریں ہاتھ کی دیکھیں تو ہو گیا خاموش.. فقیر نے میرے چہرے پہ دم کیا ہی نہیں .. تمہارے ساتھ نہیں, یہ ہماری عادت ہے.. کسی سے پیار کیا ہے تو کم کیا ہی نہیں ..

kal pe saara kaam daal k ... aaj ka din bht acha

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Ghajini

without friends :(

08:23 am :D